Disease: Basal Cell Carcinoma
Year: 2004
Investigator: Nori, et al.
Cases: 152 (83 BCC)
Sensitivity: 95.7%
Specificity: 82.9%
Reference: Nori S, Rius-Díaz F, Cuevas J, Goldgeier M, Jaen P, Torres A, González S. "Sensitivity and Specificity of Reflectance-Mode Confocal Microscopy for In Vivo Diagnosis of Basal Cell Carcinoma: a Multicenter Study". J Am Acad Dermatol. Dec 2004; 51(6):923-30.
Disease: Melanoma Year: 2004
Investigator: Gerger, et al.
Cases: 117 (27 MM)
Sensitivity: 98.2%
Specificity: 98.9%
Reference: Gerger A, Koller S, Kern T, Massone C, Steiger K, Richtig E, Kerl H, Smolle J. "Diagnostic Applicability of In Vivo Confocal Scanning Laser Microscopy in Melanocytic Skin Tumors". J Invest Dermatol. Mar 2005; 124(3):493-8.
Disease: Melanoma Year: 2005
Investigator: Pellacani, et al. Cases: 102 (37 MM)
Sensitivity: 97.3%
Specificity: 72.3%
Reference: Pellacani G, Guitera P, Longo C, Avramidis M, Sedenari S, Menzies S. “The Impact of In Vivo Reflectance Confocal Microscopy for the Diagnostic Accuracy of Melanoma and Equivocal Melanocytic Lesions”. J Invest Dermatol. Jul 2007; doi:10.1038/sj.jid.5700993.
Disease: Contact Dermatitis Year: 2005
Investigator: Astner, et al. Cases: ~80 Body Sites
Sensitivity: 52-96%
Specificity: 95-100%
Reference: Astner S, Gonzalez E, Cheung A, Rius-Diaz F, González S. "Pilot Study on the Sensitivity and Specificity of In Vivo Reflectance Confocal Microscopy in the Diagnosis of Allergic Contact Dermatitis". J Am Acad Dermatol. Dec 2005; 53(6):986-92.
Disease: Melanoma Year: 2006
Investigator: Gerger, et al. Cases: 162 (27 MM)
Sensitivity: 90.7%
Specificity: 98.9%
Reference: Gerger A, Koller S, Weger W, Richtig E, Kerl H, Samonigg H, Krippl P, Smolle J. "Sensitivity and Specificity of Confocal Laser-Scanning Microscopy for In Vivo Diagnosis of Malignant Skin Tumors". Cancer. Jul 1, 2006; 107(1):193-200.
Disease: Melanoma Year: 2007
Investigator: Pellacani, et al. Cases: 351 (136 MM)
Sensitivity: 91.9%
Specificity: 69.3%
Reference: Pellacani G, Guitera P, Longo C, Avramidis M, Sedenari S, Menzies S. “The Impact of In Vivo Reflectance Confocal Microscopy for the Diagnostic Accuracy of Melanoma and Equivocal Melanocytic Lesions”. J Invest Dermatol. Jul 2007; doi:10.1038/sj.jid.5700993.
Disease: Actinic Keratosis Year: 2007
Investigator: Ulrich, et al. Cases: 44 Test Accuracy: 97.5%
Reference: Ulrich, M, Maltausch, A, Rower-Huber, J, Gonzalez, S, Sterry W, Stockfleth, E, Astner, S. "Actinic Keratoses: non-invasive diagnosis for field cancerisation". British Journal of Dermatology. 2007; 156 (Suppl.3), 13-17.
